Turning Concepts Into Products

These technologies are currently available for financing, licensing or partnering. Please contact John Dobak, M.D. at jdobak@jakkgroup.com.

MEMS Based Heart Sensor

The JAKK group is leading the development of a novel MEM sensor that that can measure the synchrony of the heart contraction and may help improve the response rate of cardiac resynchronization therapy (CRT). CRT is a pacemaker therapy for heart failure that improves heart function through pacing by causing a more coordinated, or synchronous, contraction of the ventricles. It has been one of the most significant advances in heart failure therapy in the last 30 years. Annual CRT device sales are expected to exceed $4.5 BB in the U.S. alone by 2010.

Pharmaceutical Treatment of Regional Fat Accumulations

JAKK Group developed and recently financed an injectable pharmaceutical preparation for the reduction of fat deposits. This technology was spun out as a start-up company Lithera, Inc. (www.lithera.com). Lithera, Inc. recently received $21.5 MM in venture capital financing to further develop the technology for both medical and lifestyle indications.

Lifestyle treatments are a rapidly growing area of medicine as evidenced by the 3 million Botox® injections each year. A similar type of therapy to treat fat deposits (both medical and cosmetic) would be similarly well received. The technology developed by the JAKK Group for Lithera was a novel drug formulation of previously marketed (FDA approved) drugs that induces fat cell storage breakdown and inhibits fat cell growth. It is estimated that $3 BB per annum in the U.S. is spent on products and treatments to improve the appearance of regional fat deposits.

Pulmonary Neurostimulation

Stimulation of novel lung receptor targets involved in the control breathing and regulation of cardiovascular physiology may be an effective treatment heart failure, hypertension, asthma, and sleep apnea. For example, central sleep disturbance that occurs in heart failure can lead to severe cardiovascular dysfunction and may be treated by this technology. The therapy may also have application in obstructive sleep apnea. The estimated market potential for implantable modulation of lung receptors exceeds $1.5 BB in the U.S.

Custom AAA Endovascular Stent-Grafts

Devices and methods for liposuction including intraabdominal

Left atrial pressure relief system for heart failure